溶解气研究

Our thanks to Prof David Lloyd (Biology Dept., University of Wales, Cardiff)for this list of published papers from his research group activity

.Many of these publications illustrate the practical use and capabilityof
the HPR-40 system as a dissolved species probe.

1

Oxidative detoxification of hydrogen sulphide detected by mass spectrometry in the soil amoeba Acanthamoeba castellanii . D. Lloyd, B. Kristensen & H. Degn. J. Gen. Microbiol. 126 , 167-I70 (1981).

2

The effects of cyanide, azide, carbon monoxide and salicylhydroxamic acid on whole cell respiration of Acanthamoeba castellanii . D. Lloyd, B. Kristensen & H. Degn. J. Gen. Microbiol . 128 , 185-188 (1981).

3

Glycolysis and respiration in yeasts: The Pasteur effect studied by mass spectrometry. D. Lloyd, B. Kristensen & H. Degn. Biochem. J . 212, 749-754 (1983).

4

Glycolysis and respiration in yeasts: the effect of NH 4 + in yeasts studied by mass spectrometry. D. Lloyd, B. Kristensen & H. Degn. J. Gen. Microbiol . 129 , 2125-2127 (1983).

5

The presence of O 2 in rumen liquor and its effects on methanogenesis. R. I. Scott, N. Yarlett, K. Hillman, T. N. Williams, A. G. Williams & D. Lloyd. J. App. Bacteriol. 55 , 143-149 (1983).

6

A note on the effects of hydrogen production by the rumen protozoon Dasytricha ruminantium Schuberg. N. Yarlett, R. I. Scott, A. G Williarns & D. Lloyd. J. Appl. Bacteriol . 55 , 359-361 (1983).

7

Direct measurement of methanogenesis in anaerobic digesters by membrane inlet mass spectrometry. Scott, R. I., Williams, T. N., Whitmore, T. N. & Lloyd, D. Europ. J. Applied Microbiol. & Biotechnol . 18, 236-241 (1983).

8

Membrane inlet mass spectrometry - Measurement of dissolved gases in fermentation liquids. Lloyd, D., Scott, R. I. & Williams, T. N. Trends in Biotechnol . 1 , 60-63 (1983).

9

Direct measurement of dissolved gases in microbiological systems using membrane inlet mass spectrometry. Lloyd, D. & Scott, R. I. J. Microbiol. Methods 1 , 313-320 (1983).

10

Oxygen sensitivity of methanogenesis in rumen and anaerobic digester populations using mass spectrometry. Scott, R. I., Williams, T. N. & Lloyd, D. Biotechnol. Lett . 5 , 375-380 (1983).

11

Metronidazole inhibition of hydrogen production in vivo in drug-sensitive and resistant strains of Trichomonas vaginalis . Lloyd, D. & Kristensen, B. J. Gen. Microbiol . 131 , 849-853 (1985).

12

Comparative studies of methanogenesis in thermophilic and mesophilic digesters using membrane inlet mass spectrometry. T. N. Whitmore, M. Lazzari & D. Lloyd. Biotechnol. Lett . 7 , 283-288 (1985).

13

Measurement of dissolved gas concentrations in ovine rumen liquor in situ using a portable quadrupole mass spectrometer. K. Hillman, D. Lloyd & A. G Williams. Current Microbio l. 12 , 335-340 (1985).

14

Inhibition of H 2 production in drug-resistant and susceptible strains by a range of nitroimidazole derivatives. D. Lloyd, N. Yarlett & N. C. Yarlett. Biochem Pharmacol 35 , 61-64 (1986).

15

Aerobic bacterial denitrification: the rule rather than the exception. D. Lloyd, L. Boddy & K. J. P. Davies. FEMS Microbiol. Ecology 45 , 185-190 (1987).

16

Ferredoxin-dependent reduction of nitroimidazole derivatives in drug-resistant and susceptible strains of Trichomonas vaginalis . N. Yarlett, N. C. Yarlett and D. Lloyd. Biochem. Pharmacol. 35 , 1703-1708 (1986).

17

Hydrogen-dependent control of the continuous anaerobic digestion process. T. N. Whitmore, G. Jones & D. Lloyd. Appl. Microbiol. Biotechnol . 26 , 383-388 (1987).

18

Mass spectrometry as an ecological tool for in situ measurements of dissolved gases in sediment systems. D. Lloyd, K. J. P. Davies & L. Boddy. FEMS Microbiol. Ecol . 38 , 11-17 (1986).

19

Reduction of nitridazole by metronidazole resistant and susceptible strains of Trichomonas vaginalis. N. Yarlett, C. C. Rowlands, N. C. Yarlett, J. C. Evans & D. Lloyd. Parasitology 94 , 93-99 (1987).

20

Methanogenesis from methanol in Methanosarcina barkeri studied using membrane inlet mass spectrometry. G Ranalli, T. N. Whitmore & D. Lloyd. FEMS Microbiol. Lett . 35 , 119-123 (1986).

21

Metronidazole resistant clinical isolates of Trichomonas vaginalis maintain low intracellular metronidazole radical anion levels as a consequence of defective O 2 scavenging. D. Lloyd, N. Yarlett, N. C. Yarlett, J. Z. Pedersen & B. Kristensen. Acta Universitatis CarolinaeBiologica 30 , 521-528 (1988).

22

Mass spectrometric control of the thermophilic anaerobic digestion process based on levels of dissolved hydrogen. T. N. Whitmore & D. Lloyd. Biotechnology Letters 8 , 203-208 (1986).

23

Respiration of the hydrogenosome-containing fungus Neocalimastix patriciarum . N. Yarlett, C. Rowlands, N. C. Yarlett, J. C. Evans & D. Lloyd. Arch. Microbiol. 148 , 25-28 (1987).

24

The effects of O 2 on fermentation in Tritrichomonas foetus KV1 and its variant 1MR100 with defective hydrogenosomes. D. Lloyd, C. J. James, A. L. Lloyd, N. Yarlett & N. C. Yarlett. J. Gen. Microbiol. 133 , 1181-1187 (1987).

25

The Pasteur Effect in Yeast: mass spectrometric monitoring of O 2 uptake and CO 2 and ethanol production. D. Lloyd & C. J. James. FEMS Microbiol. Lett. 42 , 27-31 (1987).

26

Interactions between the methanogen Methanosarcina barkeri and ciliate protozoa. K. Hillman, D. Lloyd & A. G. Williams. Lett. Appl. Microbiol . 7 , 49-53 (1988).

27

Hydrogen-dependent control of the continuous thermophilic anaerobic digestion process using membrane inlet mass spectrometry. D. Lloyd, T. N. Whitmore. Lett. Appl. Microbiol. 6 , 5-10 (1987).

28

The influence of oxygen and organic hydrogen acceptors on glycolytic CO 2 production in Brettanomyces anomalous . D. M. Gaunt, H. Degn, D. Lloyd. Yeast 4 , 249-255 (1988).

29

Aerobic denitrification in Paracoccus denitrificans and Pseudomonas aeruginosa . K. J. P. Davies, D. Lloyd & L. Boddy. J. Gen. Microbiol. 135 , 2445-2451.

30

Formate and glucose stimulation of methane and hydrogen production in rumen liquor. J. E. Ellis, A. G Williams & D. Lloyd. Current Microbiol. 20 , 251-254 (1990).

31

Giardia lamblia produces alanine anaerobically but not in the presence of oxygen. T. A. Paget, M. H. Raynor, D. W. E. Shipp & D. Lloyd. Molecular. Biochem. Parasitology 42 , 63-68 (1990).

32

Trichomonas vaginalis requires traces of oxygen and high concentrations of carbon dioxide for optimal growth. T. A. Paget & D. Lloyd (1990). Molec. Biochem. Parasitol. 41 , 65-72.

33

Influence of CO 2 and low concentrations of O 2 on fermentative metabolism of the ruminal ciliate Polyplastron multivesciculatum . J. E. Ellis, P. S. McIntyre, M. Saleh, A. G. Williams & D. Lloyd. Appl. Environ. Microbiol. 57 , 1400-1407 (1991).

34

Influence of CO 2 and low concentrations of O 2 on fermentative metabolism of the rumen ciliate Dasytricha ruminantium . J. E. Ellis, P. S. McIntyre, M. Saleh, A. G. Williams & D. Lloyd. J. Gen. Microbiol . 137 , 1409-1417 (1991).

35

The parasitic flagellates Trichomonas vaginalis and Tritrichomonas foetus produce indole and dimethyldisulphide: direct characterization by membrane inlet tandem mass spectrometry. D. Lloyd, F. R. Lauritsen & H. Degn. J. Gen. Microbiol . 137 , 1743-47 (1991).

36

Identification of dissolved volatile metabolites in microbial cultures by membrane inlet tandem mass spectrometry. F. R. Lauritsen, D. Lloyd, S. Bohatka, L. T. Nielsen & H. Degn. Biological Mass Spectrometry 60 , 253-258 (1991).

37

Enzyme activity in organic solvent as a function of water activity determined by membrane inlet mass spectrometry. H. Degn, S. Bohatka & D. Lloyd. Biotechnology Techniques 6 , 161-164 (1992).

38

The influence of ruminal concentrations of O 2 on fermentative metabolism of the rumen entodiniomorphid ciliate, Eudiplodinium maggii . J. E. Ellis, P. S. McIntyre, M. Saleh, A. G Williams & D. Lloyd. Current Microbiology 23 , 245-251 (1991).

39

The effects of O 2 on fermentation in the intestinal parasite Giardia lamblia . T. A. Paget, M. L. Kelly, E. L. Jarroll, D. G Lindmark & D. Lloyd. Mol. Biochem. Parasitol. 57 , 65-72 (1992).

40

Effects of alcohols on the respiration and fermentation of aerated suspension of Baker's Yeast. H. N. Carlsen, H. Degn & D. Lloyd. J. Gen. Microbiol. 137 , 28792883 (1991).

41

Mutations in phosphofructokinases alter the control characteristics of glycolysis in vivo in Saccharomyces cerevisiae . D. Lloyd, C. J. James & P. K. Maitra. Yeast, 8 , 291-301 (1992).

42

Influence of oxygen on the fermentative metabolism of metronidazole-sensitive and resistant strains of Trichomonas vaginalis . J. E. Ellis, D. Cole and D. Lloyd. Biochem. Molec. Parasitol. 56 , 79-88 (1992).

43

Rapid method for monitoring methanogenic activities in mixed cell culture; effects of inhibitory compounds. J. Benstead, D. B. Archer and D. Lloyd. Biotechnol. Techniques 7 , 31-36.

44

Combined 13 C-NMR and mass spectrometry for non-invasive monitoring of metabolism. D. Lloyd, C. J. James, A. Chapman & J. R. Dickinson. Biotechnol. Techniques, 6 , 81-86 (1993).

45

Effects of growth with ethanol on fermentation and membrane fluidity of Saccharomyces cerevisiae . D. Lloyd, S. Morrell, H. N. Carlsen, H. Degn, P. E. James and C. C. Rowlands. Yeast 9 , 825-833 (1993).

46

Rapid and direct monitoring of volatile fermentation products in the fungus Bjerkandera adusta by membrane inlet mass spectrometry. F. R. Lauritsen, T. Kotiaho and D. Lloyd. Biolog. Mass Spectrom. 22 , 585-589 (1993).

47

Direct mass spectrometric measurement of gases in peat cores. J. Benstead and D. Lloyd. FEMS Microbiol. Ecol. 13 , 233-240 (1994).

48

Effects of oxygen, pH and nitrate concentration on denitrification by Pseudomonas species. K. L. Thomas, D. Lloyd and L. Boddy. FEMS Microbiol. Lett. 118 , 181-186 (1994).

49

Measurement of denitrification in estuarine sediment using membrane inlet mass spectrometry. K. L. Thomas and D. Lloyd. FEMS Microbiol. Ecol. 16 , 103-114 (1995).

50

Spatial and temporal variations of dissolved gases (CH 4 , CO 2 and O 2 ) in peat cores. J. Benstead and D. Lloyd. Microbial Ecology 31 (1) 57-66 (1995).

51

A MIMS miniprobe for the direct simultaneous measurement of multiple gas species. D. Lloyd, K. Thomas, D. Price, B. O'Neil, K. Oliver and T. N. Williams. J. Microbiol. Meth. (1996). 25 , 145-151.

52

A comparison of different methods for the measurement of dissolved gas gradients in waterlogged peat cores. K. L. Thomas, D. Price and D. Lloyd. J. Microbiol. Meth. 24 , 191-198 (1995).

53

Role of wetland plants in the diurnal control of methane and carbon dioxide fluxes in peat. K. L. Thomas, J. Benstead, K. L. Davies and D. Lloyd. Soil Biol. Biochem. 28 , 17-23 (1996).

54

Gas diffusion coefficient profile in peat deterrnined by modelling mass spectrometric data: implications for gas phase distribution. K. D. Stephen, J. R. M. Arah, K. L. Thomas, J Benstead and D. Lloyd. Soil Biol. Biochem (1998) 30 , 429-431.

55

Oxygen Dependent Low Temperature n6 (~12)-Desaturase Induction and Alteratio of Fatty Acid Composition in Acanthamoeba castellanii . S. V. Avery, J. Rutter, J. L. Harwood and D. Lloyd. Microbiology (1996) 142 , 2213-2221.

56

Micro-ecology of peat: minimally invasive analysis using confocal laser scannin microscopy, membrane inlet mass spectrometry and PCR-amplification of methanogen-specific gene sequences. D. Lloyd, K.L. Thomas, A. Hayes, B. Hill, B.A. Hales, C. Edwards, J. R. Saunders, D.A. Ritchie and M. Upton. FEMS Microbial. Ecol . 25 , 179-188 (1998).

57

Diurnal oscillations of gas production and effluxes (CO 2 AND CH 4 ) in cores from peat bog. K.L. Thomas, D. Lloyd, J. Benstead and S.H. Lloyd. Biol. Rhythm Res . 29 247-259 (1998).

58

Oxygen induces microsomal fatty acid ~12(n6) -desaturase independently of temperature in O2-limited cultures of Acanthamoeba castellanii (1997) Thomas, K.L., Rutter, A.J., Suller, M.T.E., Lloyd, D. & Harwood, J. FEBS Lett . 425 , 171-174.

59

Methanogenesis and CO 2 exchange in an ombrotrophic peat bog. D.Lloyd, K.L.Thomas, J.Benstead, K.L.Davies, S.H.Lloyd, J.R.M.Arah and K.D.Stephen , Atmospher. Environ. (1998). 31 , 3229-3238.

60

N 2 , N 2 O and 0 2 profiles in a Tagus estuary salt marsh sediment. Cartaxana, P and Lloyd, D. Coastal and Shelf Science 48 , 751-756.

61

Electrospray mass spectrometry for assay of erythromycin A extracted from fermentation liquor. Morgan, J., Rowlands, R. T., Joyce-Menekse, M. E., Gilbert, I. H. & Lloyd, D. Biotechnol. Techn (1998). 12 , 435-439.

62

Photosynthesis and gas dynamics in an estuarine sediment: sub-millimeter resolution profiles using membrane inlet mass spectrometry. Cowie, G & Lloyd, D.(In preparation.)

63

N itrite Inhibits Hydrogen Production and Kills the Cattle Parasite Tritric foetus. Lloyd, D & James C J (In preparation.)

64

Membrane inlet ion trap mass spectrometry for the direct measurement of dissolved gas in ecological samples. Cowie, G & Lloyd, D. J. Microbial Meth . 25 , 1-12.

65

Yeast Vitality During Cider Fermentation: Assessment By Energy Metabolism. Dinsdale, M. G, Lloyd, D., McIntyre, P. & Jarvis, B. Yeast (1999). 15 , 285-293.

66

Anoxic function for the E.coli flavohaemoglobin (Hmp): reversible binding of NO and reduction to N 2 O. Kim, S.O., Orii, Y., Lloyd, D., Hughes, M. N. and Poole, R. L. C. FEBS Lett. 445 , 389-394 (1999).

67

Kinetics, stereospecificity and expression of the malolactic enzyme. C. Authurs and D. Lloyd, Appl. Environ. Microbiol . 65 , 3360-3363 (1999).

68

Rapid and Sensitive Quantitation of Antibiotics in Fermentations by Electrospray Mass Spectrometry. Janine Morgan, Miranda E. Joyce-Menekse, Robert T. Rowlands, Ian H. Gilbert and David Lloyd (2000).

69

Extraction and identification of volatile organic substances (VOS) from Scottish peat cores. Beckmann, M. & Lloyd, D. Atmospheric Environment , (2000).

70

Mass spectrometric monitoring of gases (CO 2 , CH 4 , 0 2 ) in peat cores from Kopparas Mire, Sweden. Beckmann, M. & Lloyd, D. Gobal Change Biology , (2000)

71

Aromatic interconversions in the white-rot fungus Bjerkandera adusta . Lunding, A. Lauritsen, F. R. & Lloyd, D. Enz. Microb. Techno l (2000).

72

Tammam, J.D., Williams, A.G., Banks, J., Cowie, G & Lloyd, D. (2000). Membrane inlet mass spectrometric measurement of 0 2 and CO 2 gradients in a developing Cheddar cheese ecosystem. Int. J. Food Microbiol. [In Press].


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